The Journal of Emergency Medicine
Volume 22, Issue 3 , Pages 247-249, April 2002

Symptomatic bradycardia secondary to interaction between topical timolol maleate, verapamil, and flecainide: a case report☆

  • Travis Minish, BSc, MD

      Affiliations

    • Department of Emergency Medicine, Health Sciences Center, Winnipeg, Manitoba, Canada
    • ,
  • Anthony Herd, BSc, MD (CCFP(EM))

      Affiliations

    • Corresponding Author InformationReprint Address: Anthony Herd, BSc, MD, Adult Emergency Unit, Health Sciences Center, GF-201, 820 Sherbrook Street, Winnipeg, Manitoba R3A 1R9, Canada
    • Department of Emergency Medicine, Health Sciences Center, Winnipeg, Manitoba, Canada

Received 6 February 2001; received in revised form 19 June 2001; accepted 29 June 2001.

Abstract 

We present a case report describing an interaction between topical timolol maleate, verapamil, and flecainide resulting in symptomatic bradycardia. Adverse drug interactions, including topical medications, are relevant in the differential diagnosis of many presenting complaints.

Keywords:  drug interaction, bradycardia, timolol

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☆ Clinical Communications is coordinated by Ron M. Walls, md, of Brigham and Women’s Hospital and Harvard University Medical School, Boston, Massachusetts

PII: S0736-4679(01)00476-0

The Journal of Emergency Medicine
Volume 22, Issue 3 , Pages 247-249, April 2002

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