The Journal of Emergency Medicine
Volume 38, Issue 2 , Pages 171-174 , February 2010

Whole Bowel Irrigation and the Hemodynamically Unstable Calcium Channel Blocker Overdose: Primum Non Nocere

  • Kirk L. Cumpston, DO

      Affiliations

    • The Toxikon Consortium at Cook County Hospital, Chicago, Illinois
    • Department of Emergency Medicine, University of New Mexico, Albuquerque, New Mexico
    • ,
  • Steven E. Aks, DO

      Affiliations

    • The Toxikon Consortium at Cook County Hospital, Chicago, Illinois
    • Department of Emergency Medicine, Cook County Hospital, Chicago, Illinois
    • Corresponding Author InformationReprint Address: Steven E. Aks, do, facmt, Department of Emergency Medicine, Cook County Hospital, 1900 West Polk Street, 10th Floor, Chicago, IL 60612
    • ,
  • Todd Sigg, PHARMD

      Affiliations

    • The Illinois Poison Control Center, Chicago, Illinois
    • ,
  • Erin Pallasch, PHARMD

      Affiliations

    • The Illinois Poison Control Center, Chicago, Illinois

Received 30 August 2006 ,Revised 26 March 2007 ,Accepted 15 November 2007.

References 

  1. Tenenbein M. Whole bowel irrigation for toxic ingestion. J Toxicol Clin Toxicol. 1985;23:177–184
  2. Tenenbein M. Position statement: whole bowel irrigation (American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists). J Toxicol Clin Toxicol. 1997;35:753–762
  3. Tenenbein M, Cohen S, Sitar DS. Whole bowel irrigation as a decontamination procedure after acute drug overdose. Arch Intern Med. 1987;147:905–907
  4. Smith SW, Ling LJ, Halstenson CE. Whole-bowel irrigation as a treatment for acute lithium overdose. Ann Emerg Med. 1991;20:536–539
  5. Kirshenbaum LA, Mathews SC, Sitar DS, et al. Whole-bowel irrigation versus activated charcoal in sorbitol for the ingestion of modified-release pharmaceuticals. Clin Pharmacol Ther. 1989;46:264–271
  6. Buckley N, Dawson AH, Howarth D, et al. Slow-release verapamil poisoning: use of polyethylene glycol whole-bowel lavage and high-dose calcium. Med J Aust. 1993;158:202–204
  7. Gutierrez H, Jorgensen M. Colonic ischemia after verapamil overdose. Ann Intern Med. 1996;124:535
  8. Wax PM. Intestinal infarction due to nifedipine overdose. J Toxicol Clin Toxicol. 1995;33:725–728
  9. Fauville JP, Hantson P, Honore P, Belpaire F, Rosseel MT, Mahieu P. Severe diltiazem poisoning with intestinal pseudo-obstruction: case report and toxicological data. J Toxicol Clin Toxicol. 1995;33:273–277
  10. Sporer KA, Manning JJ. Massive ingestion of sustained-release verapamil with a concretion and bowel infarction. Ann Emerg Med. 1993;2:603–605
  11. Schultz HS, Vernon B. Intestinal pseudo-obstruction related to using verapamil. West J Med. 1989;151:556–558

PII: S0736-4679(08)00190-X

doi: 10.1016/j.jemermed.2007.11.100

The Journal of Emergency Medicine
Volume 38, Issue 2 , Pages 171-174 , February 2010

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