The Journal of Emergency Medicine
Volume 36, Issue 2 , Pages 217-219 , February 2009

Comparison of the Calculated and Measured Osmolality in Intracranial Bleeding and Head Injury Patients

  • Serefden Açıkgöz, MD

      Affiliations

    • Department of Biochemistry, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
  • ,
  • Murat Can, MD

      Affiliations

    • Department of Biochemistry, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
    • Corresponding Author InformationReprint Address: Murat Can, md, Department of Biochemistry, Karaelmas University, Kozlu, Zonguldak 67100, Turkey
  • ,
  • A. Görkem Mungan, MD

      Affiliations

    • Department of Biochemistry, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
  • ,
  • Meryem Ataymen, MD

      Affiliations

    • Department of Biochemistry, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
  • ,
  • Vildan Sümbüloglu, PhD

      Affiliations

    • Department of Biostatistics, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
  • ,
  • Sanser Gül, MD

      Affiliations

    • Department of Neurosurgery, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey

Received 12 March 2007 ,Accepted 14 November 2007.

References 

  1. Gennari FJ. Current concepts (Serum osmolality. Uses and limitations). N Engl J Med. 1984;310:102–105
  2. Khajuria A, Krahn J. Osmolality revisited—deriving and validating the best formula for calculated osmolality. Clin Biochem. 2005;38:514–519
  3. Burtis CA, Ashwood ER. Tietz textbook of clinical chemistry. 3rd edn.. Philadelphia, PA: W.B. Saunders; 1999;
  4. Morales EJG, Cariappa R, Parvin CA, Scott MG, Diringer MN. Osmole gap in neurologic-neurosurgical intensive care unit: its normal value, calculation and relationship with mannitol serum concentrations. Crit Care Med. 2004;32:986–991
  5. Sztajnkrycer MD, Scaglione JM. Falsely elevated osmol gap due to hypertonic hyponatremia. J Emerg Med. 2005;28:455–457
  6. Puliyel JM. Osmotonicity of acetoacetate: possible implications for cerebral edema in diabetic ketoacidosis. Med Sci Monit. 2003;9:BR130–BR134
  7. Krahn J, Khajuria A. Osmolality gaps: diagnostic accuracy and long term variability. Clin Chem. 2006;52:737–739
  8. Dorwart WV, Chalmers L. Comparison of methods for calculating serum osmolality form chemical concentrations, and the prognostic value of such calculations. Clin Chem. 1975;21:190–194

PII: S0736-4679(08)00202-3

doi: 10.1016/j.jemermed.2007.11.075

The Journal of Emergency Medicine
Volume 36, Issue 2 , Pages 217-219 , February 2009