The Journal of Emergency Medicine
Volume 37, Issue 2 , Pages 160-162 , August 2009

Progressive Rash After Recent Antibiotic Exposure

  • Christopher H. LeMaster, MD

      Affiliations

    • Harvard Affiliated Emergency Medicine Residency, Division of Emergency Medicine, Harvard Medical School, Boston, Massachusetts
    • ,
  • David F.M. Brown, MD

      Affiliations

    • Harvard Affiliated Emergency Medicine Residency, Division of Emergency Medicine, Harvard Medical School, Boston, Massachusetts
    • Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts
    • Corresponding Author InformationReprint Address: David F. M. Brown, md, Department of Emergency Medicine, Massachusetts General Hospital, Founders 114, 55 Fruit Street, Boston, MA 02114
    • ,
  • Eric S. Nadel, MD

      Affiliations

    • Harvard Affiliated Emergency Medicine Residency, Division of Emergency Medicine, Harvard Medical School, Boston, Massachusetts
    • Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts
    • Department of Emergency Medicine, Brigham and Women's Hospital, Boston, Massachusetts

References 

  1. Pichichero ME, Casey JR. Safe use of selected cephalosporins in penicillin-allergic patients: a meta-analysis. Otolaryngol Head Neck Surg. 2007;136:340–347
  2. Dash CH. Penicillin allergy and the cephalosporins. J Antimicrob Chemother. 1975;1(3 Suppl):107–118
  3. Petz LD. Immunologic cross-reactivity between penicillins and cephalosporins: a review. J Infect Dis. 1978;137(Suppl):S74–S79
  4. Thoburn R, Johnson JE, Cluff LE. Studies on the epidemiology of adverse drug reactions. IV. The relationship of cephalothin and penicillin allergy. JAMA. 1966;198:345–348
  5. Petz LD. Immunologic reactions of humans to cephalosporins. Postgrad Med J. 1971;47(Suppl):64–69
  6. Scholand JF, Tennenbaum JI, Cerilli GJ. Anaphylaxis to cephalothin in a patient allergic to penicillin. JAMA. 1968;206:130–132
  7. Kabins SA, Eisenstein B, Cohen S. Anaphylactoid reaction to an initial dose of sodium cephalothin. JAMA. 1965;193:165–166
  8. Kelkar PS, Li JT. Cephalosporin allergy. N Engl J Med. 2001;345:804–809
  9. Pumphrey RS, Davis S. Under-reporting of antibiotic anaphylaxis may put patients at risk. Lancet. 1999;353:1157–1158
  10. Saxon A, Beall GN, Rohr AS, Adelman DC. Immediate hypersensitivity reactions to beta-lactam antibiotics. Ann Intern Med. 1987;107:204–215
  11. Pichichero ME. A review of evidence supporting the American Academy of Pediatrics recommendation for prescribing cephalosporin antibiotics for penicillin-allergic patients. Pediatrics. 2005;115:1048–1057
  12. Gruchalla RS, Pirmohamed M. Antibiotic allergy. N Engl J Med. 2006;354:601–609
  13. Bernstein I, Gruchalla RS, Lee R, Nicklas R, Dykewicz M. Executive summary of disease management of drug hypersensitivity: a practice parameter. Ann Allergy Asthma Immunol. 1999;83:665–700
  14. Bigby M, Jick S, Jick H, Arndt K. Drug-induced cutaneous reactions: a report from the Boston Collaborative Drug Surveillance Program on 15,438 consecutive inpatients, 1975 to 1982. JAMA. 1986;256:3358–3363
  15. Nesbitt H. Leukocytoclastic vasculitis is crampin' my style. http://blog.halnesbitt.comAccessed March 2009

PII: S0736-4679(09)00387-4

doi: 10.1016/j.jemermed.2009.05.012

The Journal of Emergency Medicine
Volume 37, Issue 2 , Pages 160-162 , August 2009

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