The Journal of Emergency Medicine
Volume 38, Issue 4 , Pages 518-523 , May 2010

Do Either Corticosteroids or Antiviral Agents Reduce the Risk of Long-Term Facial Paresis in Patients with New-Onset Bell's Palsy?

  • Andrew Worster, MD, MSC

      Affiliations

    • Division of Emergency Medicine, McMaster University, Hamilton, Ontario, Canada
    • ,
  • Samuel M. Keim, MD, MS

      Affiliations

    • Department of Emergency Medicine, The University of Arizona College of Medicine, Tucson, Arizona
    • Corresponding Author InformationReprint Address: Samuel M. Keim, md, ms, Department of Emergency Medicine, The University of Arizona College of Medicine, Arizona Health Sciences Center, PO Box 245057, Tucson, AZ 84724-5057
    • ,
  • Rupinder Sahsi, MD

      Affiliations

    • Division of Emergency Medicine, McMaster University, Hamilton, Ontario, Canada
    • ,
  • The Best Evidence in Emergency Medicine (BEEM) Group

      Affiliations

    • McMaster University, Hamilton, Ontario, Canada
    • ,
  • Arthur M. Pancioli, MD

      Affiliations

    • Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio

Received 23 April 2009 ,Revised 19 June 2009 ,Accepted 1 August 2009.

References 

  1. Grzybowski A, Kaufman MH. Sir Charles Bell (1774–1842): contributions to neuro-ophthalmology. Acta Ophthalmol Scand. 2007;85:897–901
  2. Holland NJ, Weiner GM. Recent developments in Bell's palsy. BMJ. 2004;329:553–557
  3. Salinas RA, Alvarez G, Ferreira J. Corticosteroids for Bell's palsy. (idiopathic facial paralysis) Cochrane Database Syst Rev. 2004;(4):CD001942
  4. Allen D, Dunn L. Aciclovir or valaciclovir for Bell's palsy. (idiopathic facial paralysis) Cochrane Database Syst Rev. 2004;(3):CD001869
  5. Engström M, Berg T, Stjernquist-Desatnik A, et al. Prednisolone and valaciclovir in Bell's palsy: a randomised, double-blind, placebo-controlled, multicentre trial. Lancet Neurol. 2008;7:993–1000
  6. Sullivan FM, Swan IR, Donnan PT, et al. Early treatment with prednisolone or acyclovir in Bell's palsy. N Engl J Med. 2007;357:1598–1607
  7. Hato N, Yamada H, Kohno H, et al. Valacyclovir and prednisolone treatment for Bell's palsy: a multicenter, randomized, placebo-controlled study. Otol Neurotol. 2007;28:408–413
  8. Colditz GA, Miller JN, Mosteller F. How study design affects outcomes in comparisons of therapy (I: Medical). Stat Med. 1989;8:441–454

PII: S0736-4679(09)00686-6

doi: 10.1016/j.jemermed.2009.08.016

The Journal of Emergency Medicine
Volume 38, Issue 4 , Pages 518-523 , May 2010

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