The Journal of Emergency Medicine
Volume 40, Issue 4 , Pages 463-468 , April 2011

Steroids for Migraine Headaches: A Randomized Double-Blind, Two-Armed, Placebo-Controlled Trial

This work was previously presented at the American Academy of Emergency Medicine, Las Vegas, NV, 2007.

  • Frederick W. Fiesseler, DO

      Affiliations

    • Department of Emergency Medicine, Morristown Memorial Hospital, Morristown, New Jersey
    • Corresponding Author InformationReprint Address: Frederick W. Fiesseler, do, Department of Emergency Medicine (Box 8), Morristown Memorial Hospital, 100 Madison Avenue, Morristown, NJ 07962-1965
    • ,
  • Richard Shih, MD

      Affiliations

    • Department of Emergency Medicine, Morristown Memorial Hospital, Morristown, New Jersey
    • ,
  • Paul Szucs, MD

      Affiliations

    • Department of Emergency Medicine, Morristown Memorial Hospital, Morristown, New Jersey
    • ,
  • Michael E. Silverman, MD

      Affiliations

    • Department of Emergency Medicine, Morristown Memorial Hospital, Morristown, New Jersey
    • ,
  • Barnet Eskin, MD, PHD

      Affiliations

    • Department of Emergency Medicine, Morristown Memorial Hospital, Morristown, New Jersey
    • ,
  • Martin Clement, MD

      Affiliations

    • Department of Emergency Medicine, St. Clare's Hospital, Denville, New Jersey
    • ,
  • Rachna Saxena, DO

      Affiliations

    • Department of Emergency Medicine, Englewood Hospital, Englewood, New Jersey
    • ,
  • John Allegra, MD, PHD

      Affiliations

    • Department of Emergency Medicine, Morristown Memorial Hospital, Morristown, New Jersey
    • ,
  • Renee L. Riggs, DO

      Affiliations

    • Department of Emergency Medicine, University of Medicine and Dentistry of New Jersey (UMDNJ)-Robert Wood Johnson Medical School at New Brunswick, New Brunswick, New Jersey
    • ,
  • Nima Majlesi, DO

      Affiliations

    • Department of Emergency Medicine, Morristown Memorial Hospital, Morristown, New Jersey

Received 17 January 2009 ,Revised 14 May 2009 ,Accepted 29 August 2009.

References 

  1. Stewart WF, Shechter A, Rasmussen BK. Migraine prevalence: a review of population-based studies. Neurology. 1994;44(Suppl):S17–S23
  2. Kahn FY, Fiesseler FW, Cochrane D, et al. Does the incidence of headache and migraine in the emergency department vary with day of week or month of year?. Ann Emerg Med. 2004;44(Suppl):S21
  3. Schwartz BS, Stewart WF, Lipton RB. Lost workdays and decreased work effectiveness associated with headache in the workplace. J Occup Environ Med. 1997;39:320–327
  4. Colman I, Rothney A, Wright SC, et al. Use of narcotic analgesia in the emergency department treatment of migraine headaches. Neurology. 2004;62:1695–1700
  5. Urbaniak GC, Plous S. Research randomizer. www.randomizer.orgAccessed 2003
  6. Innes GD, MacPhail I, Dillon EC, Metcalfe C, Gao M. Dexamethasone prevents relapse after emergency department treatment of acute migraine: a randomized clinical trial. CJEM. 1999;1:26–33
  7. Baden EY, Hunter CL. Intravenous dexamethasone to prevent the recurrence of benign headache following discharge from the emergency department: a randomized, placebo-controlled trial. CJEM. 2006;8:393–400
  8. Jones JS, Brown MD, Bermingham M, et al. Efficacy of parenteral dexamethasone to prevent relapse after emergency department treatment of acute migraine. [abstract] Acad Emerg Med. 2003;10:542
  9. Donaldson D, Sundermann R, Jaskson R, Bastani A. Intravenous dexamethasone vs. placebo as adjunctive therapy to reduce the recurrence rate of acute migraine headaches: a multicenter double-blind placebo controlled trial. [abstract] Acad Emerg Med. 2006;13(Suppl):S16
  10. Rowe BH, Blitz S, Coleman I, Edmonds M. Dexamethasone in migraine relapse: a randomized, placebo-controlled clinical trial. [abstract] Acad Emerg Med. 2006;13(Suppl):S16–S17
  11. Silberstein SD. Practice parameter: evidence-based guidelines for migraine headache (an evidence-based review): report of the Quality Standards Committee of the American Academy of Neurology. Neurology. 2000;55:754–762
  12. Pryse-Phillips WE, Dodick DW, Edmeads JG, et al. Guidelines for the diagnosis and management of migraine in clinical practice (Canadian Headache Society). CMAJ. 1997;157:1273–1287
  13. Vinson DR. Treatment patterns of isolated benign headache in US emergency departments. Ann Emerg Med. 2002;39:215–222

PII: S0736-4679(09)00747-1

doi: 10.1016/j.jemermed.2009.08.022

The Journal of Emergency Medicine
Volume 40, Issue 4 , Pages 463-468 , April 2011

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