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Abstract
Acute renal failure secondary to nonsteroidal anti-inflammatory agents is an uncommon
occurrence, but may have serious or even lethal consequences. We present one such
reaction resulting in cardiac arrest in a 59-year-old diabetic treated with indomethacin.
Since presenting symptoms may be vague and unimpressive, one must consider this potential
complication to make an early diagnosis and intervene appropriately. In addition when
prescribing anti-inflammatory drugs such as indomethacin, one should be cautious in
patients who are predisposed to the development of acute renal failure. Risk factors
that should be considered are preexistent bepatorenal dysfunction, extracellular fluid
volume contraction, and concomitant use of nephrotoxic drugs.
Keywords
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References
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Article info
Publication history
Accepted:
June 2,
1989
Received in revised form:
May 20,
1989
Received:
June 21,
1988
Identification
Copyright
© 1990 Published by Elsevier Inc.
