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Case presentations of the Harvard emergency medicine residency| Volume 20, ISSUE 3, P285-290, April 2001

Hyperglycemic hyperosmolar nonketotic coma1

  • Michael R. Filbin
    Affiliations
    Harvard Affiliated Emergency Medicine Residency, Division of Emergency Medicine, Harvard Medical School, Boston, Massachusetts, USA
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  • David F.M. Brown
    Affiliations
    Harvard Affiliated Emergency Medicine Residency, Division of Emergency Medicine, Harvard Medical School, Boston, Massachusetts, USA

    Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
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  • Eric S. Nadel
    Correspondence
    Reprint Address: David F. M. Brown, MD, Department of Emergency Medicine, CLN-115, Massachusetts General Hospital, Boston, MA 02114
    Affiliations
    Harvard Affiliated Emergency Medicine Residency, Division of Emergency Medicine, Harvard Medical School, Boston, Massachusetts, USA

    Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA

    Department of Emergency Medicine, Brigham & Women’s Hospital, Boston, Massachusetts, USA
    Search for articles by this author
      Dr. Michael Filbin: Today’s case is that of a 46-year-old woman found unconscious on the floor of her apartment by her boyfriend who immediately called 911. Upon paramedic arrival the patient was noted to be unresponsive, lying on the bedroom floor. The boyfriend told paramedics that she had a history of bipolar disorder for which she took Valproic Acid. She had not been depressed recently and had never made a suicide attempt in the past. She had no known drug allergies. She did not smoke, drink alcohol, or use illicit drugs. The vital signs on EMS arrival included a heart rate of 148 beats per minute (bpm), blood pressure of 90/60 mm Hg, and shallow respirations of 14 breaths per minute. The Glascow Coma Scale was noted to be 4, with eyes opening to painful stimulus but without verbal or motor response.
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