Abstract
Objective: To describe the serious toxicity of a readily available solvent, diethylene
glycol (DEG). We describe a case of intentional ingestion of a wallpaper stripper
containing DEG resulting in severe multi-system organ failure. Case Report: A 27-year-old
male presented to the Emergency Department (ED) one day after ingesting wallpaper
stripper containing DEG. He developed acidosis, renal cortical necrosis, hepatocellular
injury, and severe neurologic sequelae, including cranial neuropathies and peripheral
demyelinating sensori-motor polyneuropathy. His neurologic function improved over
5 months. Discussion: Our case demonstrates the severe toxicity of DEG. DEG is present
in numerous formulations, often without proper protective packaging. DEG has been
associated with severe epidemic poisonings in the past and with the availability of
safer alternatives, DEG in consumer products should be eliminated. Conclusion: DEG
is found in numerous products. Delays in treatment can have devastating results, resulting
in death or permanent disability. The pervasive use of this compound makes further
human exposures likely.
Keywords
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Article info
Publication history
Published online: November 19, 2007
Accepted:
February 17,
2007
Received in revised form:
October 4,
2006
Received:
November 18,
2005
Identification
Copyright
© 2008 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
