Clinical communications: Adults| Volume 41, ISSUE 4, P366-368, October 2011

Acute Diaphragmatic Rupture in a Patient with Ehlers-Danlos Syndrome

  • Michael Levine
    Reprint Address: Michael Levine, MD, Department of Emergency Medicine, Brigham and Women's Hospital, 75 Francis Street, Neville House, 2nd Floor, Boston, MA 02115
    Harvard-Affiliated Emergency Medicine Residency, Brigham and Women's Hospital/Massachusetts General Hospital, Boston, Massachusetts
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  • Jonathan Adler
    Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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      Ehlers-Danlos syndrome (EDS) is a rare connective tissue disorder, usually characterized by the triad of hypermobility of the joints, hyperextensibility of the skin, and tissue fragility. Numerous gastrointestinal complications have been reported with this syndrome. However, spontaneous diaphragmatic rupture remains a very rare complication. We report a case of a 22-year-old woman with EDS who presented to the Emergency Department complaining of shortness of breath and left-sided chest pain. She was ultimately found to have a spontaneous diaphragmatic rupture after forceful emesis.


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