The patient was a 43-year-old otherwise healthy woman who presented to the Emergency
Department (ED) with complaint of 2 weeks of constant and progressively worsening
right fronto-parietal headache. She was seen in the primary care clinic the day before
presentation and was treated for presumed right maxillary sinusitis with amoxicillin-clavulanate,
ketorolac, and fluticasone. The patient awoke the morning of her ED visit with sudden
onset of the worst headache of her life. She described mild photophobia, nausea and
vomiting for the past 2 days, subjective fevers and chills, and nasal congestion.
She denied any prior history of headaches or migraines, stiff neck, vision changes,
aura, focal weakness, trauma, purulent nasal discharge, intravenous drug use, or history
of malignancy. She had no significant past medical or surgical history, and her only
regular medication was drospirenone and ethinyl estradiol, which she started 2 months
prior for oral contraception. She denied smoking, and drank alcohol socially. There
was no family history of migraines or clotting disorders.
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References
- Thrombosis of the cerebral veins and sinuses.N Engl J Med. 2005; 352: 1791-1798
- Clinical features and prognostic factors of cerebral venous sinus thrombosis in a prospective series of 59 patients.J Neurol Neurosurg Psychiatry. 2001; 70: 105-108
- Case-control study of risk of cerebral sinus thrombosis in oral contraceptive users and in patients who are carriers of hereditary prothrombotic conditions.BMJ. 1998; 316: 589-592
- Cerebral venous and sinus thrombosis.J Neurol. 2004; 251: 11-23
- Cerebral venous thrombosis: an update.Lancet Neurol. 2007; 6: 162-170
- The empty delta sign.Radiology. 2002; 224: 788-789
- MRI and MRA for diagnosis and follow up of cerebral venous thrombosis (CVT).Clin Radiol. 1997; 52: 672-679
- MRI in cerebral venous thrombosis.J Neuroradiol. 1994; 21: 81-99
- Cerebral MR venography: normal anatomy and potential diagnostic pitfalls.AJNR Am J Neuroradiol. 2000; 21: 74-78
- Emergent decompressive craniectomy in patients with fixed dilated pupils due to cerebral venous and dural sinus thrombosis: report of three cases.Neurosurgery. 1999; 45: 626-629
- Anticoagulation for cerebral sinus thrombosis.Cochrane Database Syst Rev. 2002; (CD002005)
- Heparin treatment in sinus venous thrombosis.Lancet. 1991; 338: 597-600
- Randomized, placebo-controlled trial of anticoagulant treatment with low-molecular-weight heparin for cerebral sinus thrombosis.Stroke. 1999; 30: 484-488
- Cerebral venous thrombosis: combined intrathrombus rtPA and intravenous heparin.Stroke. 1999; 30: 489-494
- Combined venous sinus angioplasty and low-dose thrombolytic therapy for treatment of hemorrhagic transverse sinus thrombosis in a pediatric patient.J Pediatric Hematol Oncol. 2006; 28: 196-199
- Rheolytic catheter thrombectomy, balloon angioplasty, and direct recombinant tissue plasminogen activator thrombolysis of dural sinus thrombosis with preexisting hemorrhagic infarctions.Am J Neuroradiol. 2004; 25: 1807-1811
- Thrombolytics for cerebral sinus thrombosis: a systematic review.Cerebrovasc Dis. 2003; 15: 159-166
- Cerebral venous congestion as indication for thrombolytic treatment.Cardiovasc Intervent Radiol. 2007; 30: 675-687
- Cerebral venous thrombosis: nothing, heparin, or local thrombolysis?.Stroke. 1999; 30: 481-483
- Adjunctive rheolytic thrombectomy for central sinus thrombosis.Neurosurgery. 2007; 60: E577-E578
- Nonrandomized comparison of local urokinase thrombolysis versus systemic heparin anticoagulation for superior sagittal sinus thrombosis.Stroke. 2001; 32: 2310-2317
- Urokinase treatment of sagittal sinus thrombosis with venous hemorrhagic infarction.J Stroke Cerebrovasc Dis. 1998; 7: 421-425
Article info
Publication history
Published online: February 24, 2009
Accepted:
November 29,
2008
Received in revised form:
November 18,
2008
Received:
July 3,
2008
Identification
Copyright
© 2011 Elsevier Inc. Published by Elsevier Inc. All rights reserved.