Chancroid is a sexually transmitted disease caused by Haemophilus ducreyi. It presents as painful, purulent genital lesions, often with associated painful
inguinal lymphadenopathy or bubo formation (
1
). This painful lymphadenopathy occurs in approximately half of patients with chancroid
(
2
). This disease is most commonly seen in developing countries, and in immunocompromised
patients, specifically those with human immunodeficiency virus (HIV)/acquired immune
deficiency syndrome, as it has been shown to be a cofactor in the transmission of
HIV-1 (
2
,
3
). There have also been reports of outbreaks of chancroid found within the United
States (US) in sex workers and others who have sex for money or drugs. It also tends
to have male predominance (
3
). There were 23 cases of chancroid reported to the US Centers for Disease Control
in 2007 (
4
). Diagnosis of chancroid is based on physical examination, Gram's stain showing Gram-negative
coccobacillus, culture, which is approximately 75% sensitive, and histopathology (
2
,
3
). Treatment usually consists of azithromycin orally or ceftriaxone intramuscularly
(
1
).To read this article in full you will need to make a payment
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References
- Marx J.A. Hockberger R.S. Walls R.M. Rosen's emergency medicine. 6th edn. Mosby, Inc, Philadelphia, PA2006
- Chancroid: clinical manifestation, diagnosis, and management.Sex Transm Infect. 2003; 79: 68-71
- Chancroid: contemporary appraisal.Int J Dermatol. 2003; 42: 182-190
- Sexually transmitted diseases surveillance, 2007.(Accessed August 2009)
- Recent changes in the epidemiology of genital ulcer disease in the United States, the crack cocaine connection.Sex Transm Dis. 1994; 21: S76-S80
- Chancroid epidemiology in New Orleans men.J Infect Dis. 1995; 172: 446-452
- Multistrain outbreak of chancroid in San Fransisco, 1989–1991.J Infect Dis. 1993; 163: 1106-1111
- Chancroid: results from an outbreak in Houston, Texas.South Med J. 1990; 83: 1384-1389
Article info
Publication history
Published online: November 18, 2009
Identification
Copyright
© 2011 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
