Prolonged Coma in a Child Due to Hashish Ingestion with Quantitation of THC Metabolites in Urine



      Cannabinoid-containing substances are commonly abused worldwide. Significant toxicity from these substances is uncommon in adults but can result in significant symptoms in children; these symptoms are usually short-lived.


      To report a case of prolonged mental status alteration of more than 2 days in a child who ingested hashish.

      Case Report

      A 14-month-old child presented comatose to a pediatric emergency department after ingestion of hashish; she did not regain consciousness for more than 48 h. Quantitative testing of the child’s urine for a tetrahydrocannabinol metabolite revealed a markedly elevated level, the decline of which coincided with the child’s clinical improvement.


      Significant ingestion of cannabinoid-containing substances is capable of causing prolonged symptoms (including coma) in children.


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