MEMC VI Abstracts| Volume 41, ISSUE 2, P211, August 2011

Etoricoxib Prevents ‘First of Ramadan Headache’

      Religious fasting is associated with headache. This has been documented as “First of Ramadan Headache” and “Yom Kippur Headache.” Rofecoxib (Vioxx®; Merck) and etoricoxib, both Cox-2 inhibitors with 17- and 22-h half-lives, respectively, have been shown to be effective in preventing fasting headache when taken just before the 25-h Yom Kippur fast. Rofecoxib is no longer available. We hypothesized that etoricoxib would also be effective in preventing fasting headache during the dawn-to-dusk Ramadan fast.
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