Selected Topics: Toxicology| Volume 43, ISSUE 4, P674-676, October 2012

Reversible Cerebellar Dysfunction Associated with Ciguatera Fish Poisoning

Published:February 13, 2012DOI:



      Ciguatera-fish poisoning (or ciguatera) is a common but underdiagnosed food-borne illness related to fish consumption that is characterized by nausea, vomiting and neurologic symptoms such as tingling in the fingers or toes.


      We describe the case of a young man who suffered from diarrhea and abdominal pain after eating raw fish and who also developed severe ataxia with spontaneous downbeat and perverted head-shaking nystagmus.

      Case report

      The patient experienced visual fixation suppression failure during the bithermal caloric test and bilateral smooth-pursuit impairment. Oculomotor findings suggested dysfunction of the vestibulocerebellum, especially the flocculus.


      These findings suggest that both the peripheral and the central nervous systems can be involved in ciguatera.


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