Abstract
Background
Evans' syndrome is an uncommon condition defined by the combination (either simultaneously
or sequentially) of immune thrombocytopenia purpura and autoimmune hemolytic anemia
with a positive direct antiglobulin test in the absence of known underlying etiology.
Objectives
We present a case of Evans' syndrome following influenza vaccination.
Case Report
A 50-year-old man with no prior medical history developed Evans' syndrome 4 days after
receiving influenza immunization. The patient improved following treatment with oral
prednisone and intravenous immunoglobulin.
Conclusion
Influenza vaccine is one of the most commonly used vaccines worldwide, with millions
of people being vaccinated annually. Despite its wide use, only sparse information
has been published concerning any hematological effects of this vaccine. The rarity
of such effects supports the safety of using this vaccine.
Keywords
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Article Info
Publication History
Published online: July 16, 2012
Accepted:
January 18,
2012
Received in revised form:
July 14,
2011
Received:
February 7,
2011
Footnotes
Reprints are not available.
Identification
Copyright
© 2013 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
