Albuterol is a potent and selective β2-adrenoreceptor agonist widely used in the treatment
of asthma. The mechanism of action of albuterol is thought to be mediated via stimulation
of cyclic adenosine monophosphate production by activation of the enzyme adenyl cyclase
(
1
). The systemic clearance of albuterol is by renal excretion (
2
). Peak plasma concentrations of albuterol occur approximately 2–2.5 h after ingestion
(
). After oral administration, 58–78% of the dose is excreted in the urine within 24
h (
4
).Ventolin product information v.1.0. Glaxo Smith Kline 2007. Available at: http://www.gsk.com.au/resources.ashx/prescriptionmedicinesproductschilddatadownloads/1123/File/1D60A6F0DAC0BEFCE46763C9BF1709E0/Ventolin_Syrup_CMI.pdf. Accessed February 25, 2013.
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References
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Article info
Publication history
Published online: March 07, 2013
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© 2013 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
