Abstract| Volume 48, ISSUE 4, P521, April 2015

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A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke

Berkhemer OA, Fransen PS, Beumer D, et al. N Engl J Med 2015;372:11−20.
      While intravenous alteplase administered within 4.5 h of symptom onset has been demonstrated to be efficacious in reperfusion of acute ischemic stroke and to improve outcomes, there have been no studies on the effects of directed intraarterial therapy on functional outcomes. This study assessed whether intraarterial therapy plus usual care would be more effective than usual care alone in acute ischemic events.
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