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Hemoptysis? Try Inhaled Tranexamic Acid

  • Stephanie Komura
    Affiliations
    Department of Emergency Medicine, Zuckerberg San Francisco General Hospital, San Francisco, California
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  • Robert M. Rodriguez
    Affiliations
    Department of Emergency Medicine, Zuckerberg San Francisco General Hospital, San Francisco, California

    Department of Emergency Medicine, University of California, San Francisco, California
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  • Christopher R. Peabody
    Correspondence
    Reprint Address: Christopher R. Peabody, md, mph, Department of Emergency Medicine, University of California, 505 Parnassus Avenue, San Francisco, CA 94143
    Affiliations
    Department of Emergency Medicine, Zuckerberg San Francisco General Hospital, San Francisco, California

    Department of Emergency Medicine, University of California, San Francisco, California
    Search for articles by this author

      Abstract

      Background

      Tranexamic acid (TXA) is a synthetic anti-fibrinolytic agent used to prevent and treat various bleeding complications. In many studies, investigators have evaluated its utility and safety orally, intravenously, and topically, but few studies have described the potential benefits of nebulized TXA.

      Case Report

      We present a case of massive hemoptysis treated with nebulized TXA in the emergency department (ED) that led to the cessation of bleeding and avoidance of endotracheal intubation.

      Why Should an Emergency Physician Be Aware of This?

      In massive hemoptysis, rapidly available nebulized TXA may be considered a therapeutic option, serving either as primary therapy or as a bridge until other definitive therapies can be arranged.

      Keywords

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