The diagnosis of pulmonary embolism (PE) remains a challenge in the emergency department (ED) with computed tomographic pulmonary angiography (CTPA) being the test of choice to confirm the diagnosis. The pulmonary embolism rule-out criteria (PERC) clinical decision-making tool is often applied to patients in the ED to exclude low risk patients from over-testing with CTPA. Observational studies of the PERC have demonstrated it is safe but there has never been a prospective trial to validate its safety in ruling out PE.
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