Clenbuterol is a long-acting β-adrenergic agonist that is not Food and Drug Administration–approved for use in the United States, but may be obtained without a prescription from various unregulated sellers. It has seen increasing use as a performance-enhancing drug for sports. Literature on pediatric toxicity and treatment is limited.
We report a case of a 2-year-old female presenting after an exploratory ingestion of clenbuterol.
Why Should an Emergency Physician Be Aware of This?
Use of performance-enhancing agents is increasing and physicians should be aware of the potential toxicity of intentional and unintentional ingestions of β-adrenergic agonists. Patients may exhibit nausea, vomiting, tremor, tachycardia, and hypotension, along with laboratory abnormalities, including hyperglycemia, hypophosphatemia, hypokalemia, and hyperglycemia. Hypotension might not respond to adrenergic agents and may require administration of β-adrenergic antagonists to maintain adequate perfusion.
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Published online: September 04, 2019
Accepted: June 15, 2019
Received in revised form: June 3, 2019
Received: April 18, 2019
Drs. Bonney, Hatten, and Wang contributed to the writing of the manuscript. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.
© 2019 Elsevier Inc. All rights reserved.