Abstract| Volume 57, ISSUE 4, P591, October 2019

C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations

Butler CC, Gillespie D, White P, et al. The New England Journal of Medicine. 2019; 381:111-20
      In the United States, 6.4% of the population carries a diagnosis of chronic obstructive pulmonary disease (COPD) and it was the third leading cause of death in 2014. Approximately 75% of these patients present at least once a year to a provider for COPD exacerbation and most of these receive antibiotics. However, it is well known that antibiotics can have adverse effects and available evidence suggests that antibiotics are not always necessary for COPD exacerbation. The objective of this study was to determine if point of care (POC) CRP utilization to guide antibiotic therapy for COPD exacerbations in the primary care setting can reduce antibiotic use without harm.
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