Research shows that administration of tranexamic acid (TXA) in severely injured trauma
patients can decrease mortality as well as the amount of blood products required.
Morbidity and mortality is high for patients with traumatic brain injuries (TBIs).
The theory is that progressive of intracranial bleeding, cerebral edema and cerebral
ischemia may contribute to the poor outcomes for TBI patients. There have been studies
looking at the progression of intracranial bleeding in patients with TBIs after receiving
TXA, however these studies have not thoroughly evaluated the effect on clinical outcomes.
The goal of this study was to compare neurological outcomes in adult trauma patients
who received TXA versus those who did not receive TXA.
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© 2019 Published by Elsevier Inc.
