Advertisement

The early identification of disease progression in patients with suspected infection presenting to the emergency department: a multi-centre derivation and validation study

Saeed K, Wilson DC, Bloos F, et al. Critical Care. 2019;23(40).
      The early identification of sepsis is a national focus in emergency medicine. The clinician toolbox currently contains biomarkers and clinical scores to help aid in deciding the likelihood of the presence of infection and corresponding severity. These biomarkers include procalcitonin (PCT), lactate, and c-reactive protein (CRP). Clinical scoring tools include the Systemic Inflammatory Response Syndrome (SIRS) score, Sequential Organ Failure Assessment (SOFA) score, and quick SOFA (qSOFA) score. The authors of the study address the utility of these biomarkers and scoring tools, in addition to a newer novel biomarker, mid-regional proadrenomedullin (MR-proADM), in patients presenting to the emergency department with suspected infection, with a more specific aim to identify those at risk for disease progression and mortality versus patients with uncomplicated infections appropriate for out-patient treatment.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of Emergency Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect