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Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest, A Randomized Clinical Trial. Belohlavek JB, Smalcova J, Rob, D, et al. JAMA Network Open. Feb 22, 2022; PMID: 35191923, DOI 10.1001/jama.2022.1025

        Out of hospital cardiac arrest (OHCA) is associated with significant morbidity and mortality, with some studies showing that only 50% of patients who have return of spontaneous circulation (ROSC) during initial resuscitation will have neurologically favorable outcomes. Of those who do not achieve ROSC the odds of survival are often less than 4%. Given these statistics, many have wondered whether providing temporary circulatory support via extracorporeal cardiopulmonary resuscitation (ECPR) would improve outcomes.
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